{"id":39,"date":"2019-07-10T15:51:46","date_gmt":"2019-07-10T18:51:46","guid":{"rendered":"https:\/\/www.ufsm.br\/laboratorios\/latox\/?page_id=39"},"modified":"2019-07-10T15:52:13","modified_gmt":"2019-07-10T18:52:13","slug":"analises","status":"publish","type":"page","link":"https:\/\/www.ufsm.br\/laboratorios\/latox\/analises","title":{"rendered":"AN\u00c1LISES"},"content":{"rendered":"\n<p><span style=\"color: #000000\"><strong>AS AN\u00c1LISES TOXICOL\u00d3GICAS REALIZADAS PELO LATOX ATENDEM \u00c0 TR\u00caS \u00c1REAS DA TOXICOLOGIA: MEDICAMENTOS, SOCIAL E OCUPACIONAL, AUXILIANDO NOS DIAGN\u00d3STICOS DE INTOXICA\u00c7\u00d5ES CR\u00d4NICAS E AGUDAS<\/strong><\/span><\/p>\n<div id=\"Layer6\">\n<p align=\"center\"><span style=\"color: #000000\"><strong>TOXICOLOGIA DE MEDICAMENTOS:<\/strong><\/span><\/p>\n<p align=\"center\"><span style=\"color: #000000\"><strong>Aux\u00edlio diagn\u00f3stico em intoxica\u00e7\u00f5es agudas e na motoriza\u00e7\u00e3o terap\u00eautico.<\/strong><\/span><\/p>\n<\/div>\n<div id=\"Layer7\">\n<table border=\"1\" width=\"75%\" align=\"center\">\n<tbody>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong>EXAME<\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong>AMOSTRA<\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong>T\u00c9CNICA<\/strong><\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong><a style=\"color: #000000\" href=\"http:\/\/coral.ufsm.br\/latox\/analises\/analises.htm#paracetamol\">\u00c1lcool<\/a><\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Sangue total<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">M\u00e9todo. Nicloux<\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong><a style=\"color: #000000\" href=\"http:\/\/coral.ufsm.br\/latox\/analises\/analises.htm#paracetamol\">Anfetaminas<\/a><\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">P\u00f3\/ Soro\/ Plasma\/ Urina<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">CCD\/HPLC\/Imunocromatografia<\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong><a style=\"color: #000000\" href=\"http:\/\/coral.ufsm.br\/latox\/analises\/analises.htm#paracetamol\">Cafe\u00edna<\/a><\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Soro\/ Plasma<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Espectrofotometria<\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong><a style=\"color: #000000\" href=\"http:\/\/coral.ufsm.br\/latox\/analises\/analises.htm#paracetamol\">Coca\u00edna\u00a0<\/a><br \/><\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">P\u00f3\/ Soro\/ Plasma\/ Urina<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">CCD \/ Imunocromatografia<\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong><a style=\"color: #000000\" href=\"http:\/\/coral.ufsm.br\/latox\/analises\/analises.htm#paracetamol\">Estricnina<\/a><br \/><\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Conte\u00fado g\u00e1strico\/ v\u00edsceras\u00a0<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">CCD<\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong><a style=\"color: #000000\" href=\"http:\/\/coral.ufsm.br\/latox\/analises\/analises.htm#paracetamol\">Maconha<\/a><\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Erva\/ soro\/ plasma\/ urina<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">CCD \/ Imunocromatografia<\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong><a style=\"color: #000000\" href=\"http:\/\/coral.ufsm.br\/latox\/analises\/analises.htm#paracetamol\">Morfina<\/a><br \/><\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Soro<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">CCD \/ Imunocromatografia<\/span><\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div id=\"Layer8\">\n<div align=\"center\"><span style=\"color: #000000\"><strong>TOXICOLOGIA OCUPACIONAL:<\/strong><\/span><\/div>\n<p align=\"center\"><span style=\"color: #000000\"><strong>An\u00e1lise de indicadores Biol\u00f3gicos de Exposi\u00e7\u00e3o (IBE) como acompanhamento de indiv\u00edduos profissionalmente expostos \u00e0 agentes qu\u00edmicos que podem levar \u00e0 intoxica\u00e7\u00f5es cr\u00f4nicas<br \/><\/strong><\/span><\/p>\n<\/div>\n<div id=\"Layer9\">\n<table border=\"1\" width=\"76%\" align=\"center\">\n<tbody>\n<tr>\n<td width=\"30%\">\n<div align=\"center\"><span style=\"color: #000000\"><strong>EXAME<\/strong><\/span><\/div>\n<\/td>\n<td width=\"21%\">\n<div align=\"center\"><span style=\"color: #000000\"><strong>AMOSTRA<br \/><\/strong><\/span><\/div>\n<\/td>\n<td width=\"20%\">\n<div align=\"center\"><span style=\"color: #000000\"><strong>T\u00c9CNICA\u00a0<br \/><\/strong><\/span><\/div>\n<\/td>\n<td width=\"29%\">\n<div align=\"center\"><span style=\"color: #000000\"><strong>AGENTES QU\u00cdMICOS<\/strong><\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong>\u00c0c. Delta-Aminolevul\u00ednico (ALA U)<\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Urina<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Espectrofotometria<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Chumbo<\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong>Meta-hemoglobina (MHb)<br \/><\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Sangue c\/ heparina<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Espectrofotometria<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Anilina, Nitrobenzeno, Nitrotolueno, Clorados, \u00d3xido N\u00edtrico<\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong>Colinesterase<br \/><\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Soro<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Espectrofotometria<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Organofosforados e Carbamatos<\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong>\u00c1c. Trans-trans muc\u00f4nico<br \/><\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Urina<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">HPLC<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Benzeno<\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong>\u00c1cido Hip\u00farico<\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Urina<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">HPLC<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Tolueno<\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong>\u00c1cido Metilhip\u00farico<br \/><\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Urina<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">HPLC<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Xileno<\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong>2,5 Hexanediona<br \/><\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Urina<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">HPLC<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Hexano<\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong>Chumbo<br \/><\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Sangue total\/ Urina<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">AAS\u00a0<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Chumbo<\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong>Merc\u00fario<br \/><\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Urina<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">AAS\u00a0<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Merc\u00fario<\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong>C\u00e1dmio<\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Sangue total\/ Urina<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">AAS<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">C\u00e1dmio<\/span><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"center\"><span style=\"color: #000000\"><strong>Sel\u00eanio<\/strong><\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Soro<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">AAS<\/span><\/div>\n<\/td>\n<td>\n<div align=\"center\"><span style=\"color: #000000\">Sel\u00eanio<\/span><\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div align=\"center\">\u00a0<\/div>\n<\/div>\n<div id=\"Layer10\">\n<div align=\"center\"><span style=\"color: #000000\"><strong>AS AN\u00c1LISES TOXICOL\u00d3GICAS REALIZADAS PELO LATOX ATENDEM \u00c0 TR\u00caS \u00c1REAS DA TOXICOLOGIA: MEDICAMENTOS, SOCIAL E OCUPACIONAL, AUXILIANDO NOS DIAGN\u00d3STICOS DE INTOXICA\u00c7\u00d5ES CR\u00d4NICAS E AGUDAS<br \/><\/strong><\/span><\/div>\n<\/div>\n<div id=\"Layer11\"><span style=\"color: #000000\"><strong>O<a id=\"#paracetamol\" style=\"color: #000000\" name=\"#paracetamol\"><\/a>\u00a0paracetamol<\/strong>\u00a0ou acetaminofeno \u00e9 um medicamento de uso freq\u00fcente devido \u00e0 sua a\u00e7\u00e3o forte a\u00e7\u00e3o antipir\u00e9tica, a\u00e7\u00e3o analg\u00e9sica m\u00e9dia. Em doses elevadas, pode causar grave intoxica\u00e7\u00e3o hep\u00e1tica e morte.<\/span>\n<p><span style=\"color: #000000\"><strong>Os benzodiazep\u00ednicos<\/strong>\u00a0e barbit\u00faricos t\u00eam a\u00e7\u00e3o depressora do SNC e s\u00e3o indicados especialmente como ansiol\u00edticos e anticonvulsivantes. No entanto, o seu uso indiscriminado pode levar a depend\u00eancia e, doses excessivas \u00e0 intoxica\u00e7\u00e3o agudas podendo levar \u00e0 morte.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Os salicilatos<\/strong>\u00a0pertencem ao grupo de f\u00e1rmacos com finalidade analg\u00e9sica, antit\u00e9rmica e antiinflamat\u00f3ria. Atualmente, esses f\u00e1rmacos s\u00e3o classificados como antiinflamat\u00f3rios n\u00e3o ester\u00f3ides (AINE), est\u00e3o entre os mais utilizados no mundo, com mais de 35 dispon\u00edveis para uso cl\u00ednico. Os efeitos t\u00f3xicos mais comuns ocorrem principalmente no trato gastrintestinal, nos sistemas hematol\u00f3gicos e renal, al\u00e9m do hep\u00e1tico em menor grau.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>A coca\u00edna<\/strong>\u00a0\u00e9 um dos alcal\u00f3ides presentes nas folhas do g\u00eanero Erytroxylium denominada vulgarmente de coca. \u00c9 um potente anest\u00e9sico local e potente estimulante do SNC, raz\u00e3o pela qual \u00e9 utilizada como droga de abuso.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>A maconha<\/strong>\u00a0(Cannabis sativa) ocupa um dos principais lugares dentre as drogas il\u00edcitas\u00a0mais usadas atualmente. O princ\u00edpio ativo mais importante \u00e9 o \u00ea9 THC. Os efeitos desta droga podem ser os mais variados, desde euforia a excita\u00e7\u00e3o do estado de \u00e2nimo.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>A estricnina<\/strong>\u00a0\u00e9 o principal alcal\u00f3ide da Nux-vomica \u00e9 um poderoso convulsivante, aumenta a excitabilidade reflexa por inibi\u00e7\u00e3o do per\u00edodo refrat\u00e1rio normal das c\u00e9lulas das hastes posteriores da medula. Causa freq\u00fcente de suic\u00eddio e homic\u00eddio.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>O \u00e1lcool<\/strong>\u00a0\u00e9 uma das subst\u00e2ncias psicoativas mais consumidas pela sociedade e como conseq\u00fc\u00eancia deste uso, acidentes de tr\u00e2nsito ou de trabalho, hepatopatias e tamb\u00e9m os quadros de depend\u00eancia. Estima-se que, no Brasil, uma em cada dez tenha problemas devido ao uso abusivo do \u00e1lcool, preval\u00eancia alta e que poucas patologias igualam. O \u00e1lcool \u00e9 considerado um depressor do sistema nervoso central e este \u00e9 o \u00f3rg\u00e3o mais rapidamente afetado pelo \u00e1lcool quando comparado a qualquer outro \u00f3rg\u00e3o ou sistema. O \u00e1lcool causa seda\u00e7\u00e3o, diminui\u00e7\u00e3o da ansiedade, fala pastosa, ataxia, preju\u00edzo da capacidade de julgamento e desinibi\u00e7\u00e3o do comportamento.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>A cafe\u00edna<\/strong>\u00a0est\u00e1 presente naturalmente em muitos alimentos como caf\u00e9, alguns ch\u00e1s, no guaran\u00e1, cacau, alguns refrigerantes, \u201cbebidas energ\u00e9ticas\u201d e algumas formula\u00e7\u00f5es farmac\u00eauticas. Apesar de ter seu uso bastante aceito na sociedade, a cafe\u00edna est\u00e1 inclu\u00edda na lista de subst\u00e2ncias proibidas do Comit\u00ea Ol\u00edmpico Internacional. A cafe\u00edna tem efeito diur\u00e9tico e estimulante sobre diversos sistemas do organismo humano. Em intoxica\u00e7\u00f5es graves ocorrem n\u00e1useas, v\u00f4mitos, taquicardia, hiperventila\u00e7\u00e3o, acidose metab\u00f3lica, hipocalemia, convuls\u00f5es, del\u00edrio, coma e morte por parada respirat\u00f3ria. A depend\u00eancia e s\u00edndrome de abstin\u00eancia tamb\u00e9m s\u00e3o consideradas efeitos t\u00f3xicos importantes.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>A morfina<\/strong>\u00a0\u00e9 o prot\u00f3tipo dos opi\u00e1ceos e tem sido usada na cl\u00ednica m\u00e9dica, principalmente no combate \u00e0 dor visceral intensa. A intoxica\u00e7\u00e3o aguda pela morfina geralmente \u00e9 resultado de doses cl\u00ednicas excessivas, superdose acidental em farmacodependentes ou por tentativa de suic\u00eddio. A morte quase sempre ocorre por insufici\u00eancia respirat\u00f3ria.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>A cinarizina<\/strong>\u00a0\u00e9 um antihistam\u00ednico e antiespasm\u00f3geno utilizado para o tratamento de dist\u00farbios cerebrais e insufici\u00eancia vascular perif\u00e9rica. \u00c9 prescrita para v\u00e1rias doen\u00e7as e uma s\u00e9rie de sintomas, entretanto, \u00e9 uma droga t\u00f3xica podendo causar tonturas, apatia, enxaqueca, sonol\u00eancia, hipot\u00f4nia e v\u00f4mitos.<\/span><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>AS AN\u00c1LISES TOXICOL\u00d3GICAS REALIZADAS PELO LATOX ATENDEM \u00c0 TR\u00caS \u00c1REAS DA TOXICOLOGIA: MEDICAMENTOS, SOCIAL E OCUPACIONAL, AUXILIANDO NOS DIAGN\u00d3STICOS DE INTOXICA\u00c7\u00d5ES CR\u00d4NICAS E AGUDAS TOXICOLOGIA DE MEDICAMENTOS: Aux\u00edlio diagn\u00f3stico em intoxica\u00e7\u00f5es agudas e na motoriza\u00e7\u00e3o terap\u00eautico. EXAME AMOSTRA T\u00c9CNICA \u00c1lcool Sangue total M\u00e9todo. Nicloux Anfetaminas P\u00f3\/ Soro\/ Plasma\/ Urina CCD\/HPLC\/Imunocromatografia Cafe\u00edna Soro\/ Plasma Espectrofotometria Coca\u00edna\u00a0 [&hellip;]<\/p>\n","protected":false},"author":115,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-39","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.ufsm.br\/laboratorios\/latox\/wp-json\/wp\/v2\/pages\/39","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ufsm.br\/laboratorios\/latox\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ufsm.br\/laboratorios\/latox\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ufsm.br\/laboratorios\/latox\/wp-json\/wp\/v2\/users\/115"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ufsm.br\/laboratorios\/latox\/wp-json\/wp\/v2\/comments?post=39"}],"version-history":[{"count":0,"href":"https:\/\/www.ufsm.br\/laboratorios\/latox\/wp-json\/wp\/v2\/pages\/39\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.ufsm.br\/laboratorios\/latox\/wp-json\/wp\/v2\/media?parent=39"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ufsm.br\/laboratorios\/latox\/wp-json\/wp\/v2\/categories?post=39"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ufsm.br\/laboratorios\/latox\/wp-json\/wp\/v2\/tags?post=39"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}